4.7/5 based on 137,135 reviews

Over 18 Million Happier Days

"With over 30 years of brain imaging and clinical research, I created BrainMD to deliver superior science-backed supplements for your brain."

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Daniel G. Amen, MD

Founder & Chief Visionary Officer, BrainMD

Dr. Daniel Amen is a double board-certified psychiatrist, 20-time national bestselling author, and one of the most influential voices in brain health. He’s the founder of Amen Clinics, home to the world’s largest database of brain scans related to behavior, with over 300,000 scans and counting.

Through his groundbreaking research, bestselling books, and BrainMD’s doctor-developed supplements, Dr. Amen has helped millions improve their memory, mood, focus, and mental well-being.

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Hear It From Real Customers

70% of dogs over

Supported by Clinical Research

SAFFRON SUPPORTS POSITIVE MOOD +

Clinical studies in healthy adults

affron® saffron extract has been shown in human trials to help support mood and emotional well-being.

SAFFRON HELPS PROMOTE CALM +

Clinical research in adolescents

Controlled research shows saffron extract can help encourage calmness and balanced mood in youth.

CURCUMIN SUPPORTS HEALTHY THINKING +

Studied in older adults

Research shows curcumin supplementation supports cognitive performance and healthy mood in aging populations.

CURCUMIN HELPS MEMORY & FOCUS +

Clinical study in adults

A published trial found curcumin supported memory, attention, and overall brain health in non-demented adults.

ZINC HELPS SUPPORT MOOD +

Human & animal research

Studies suggest maintaining healthy zinc levels plays a role in emotional balance and calmness.

#1 For Brain Health

#1 For Brain Health

Backed by 30+ years of research, 60+ MDs & 300,000+ brain scans.*

Doctor-Recommended

Doctor-Recommended

Formulated by Dr. Daniel Amen and leading brain health experts.

Clinically Backed

Clinically Backed

Clinically studied ingredients. Backed by science. Proven to work.

HSA/FSA Eligible

HSA/FSA Eligible

Use pre-tax dollars to support your brain, body, and daily health.

FORMULATED TO SUPPORT:

Body & Mind Response*

Body & Mind Response*

Rest*

Rest*

Focus*

Focus*

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Healthier, Happier YOU*

Clinically Dosed. Doctor Trusted. Loved Worldwide.*

Most saffron supplements stop at mood. Happy Saffron Plus® goes further, targeting mood, memory, libido, stress, and sleep with three highly bioavailable, research-backed ingredients that work better together.*

✔ affron® Saffron Extract: The only saffron with 10+ human clinical studies on mood, stress, and sleep.

✔ Longvida® Curcumin: 285x more bioavailable than standard curcumin and clinically shown to enhance memory within hours.*

✔ Zinc Glycinate: An essential mineral that supports mood, hormones, and brain health.*

This formula isn’t just well-dosed, it’s strategically dosed. Each ingredient amplifies the effects of the others for a synergistic boost you can feel, without hormones, SSRIs, or side effects.*